The Assessment of the Effectiveness of Combined Angiotensin II Receptor Antagonists and Cardiac Glycosides in the Treatment of Hypertension Complicated by Chronic Heart Failure
Keywords:
Hypertension, Chronic Heart Failure, Renal Function, Cardiac Performance, DiuresisAbstract
Hypertension and chronic heart failure (CHF) are closely linked conditions contributing to significant cardiovascular morbidity and mortality. This study evaluates a combined therapeutic approach in managing CHF stage II B (NUNA III FK), focusing on cardiac function, renal performance, and clinical symptoms. The treatment resulted in an 8.5% increase in left ventricular ejection fraction, improved renal function as evidenced by a rise in glomerular filtration rate from 98 to 110 mL/min, and optimized hemodynamic parameters with reductions in systolic and diastolic blood pressure. Diuresis improved significantly, alongside reductions in dyspnea and peripheral edema. Electrocardiographic and echocardiographic evaluations, paired with monitoring plasma potassium levels and urine output, provided a comprehensive assessment of therapy efficacy. Despite short-term findings, this approach highlights the need for long-term research to confirm its broader applicability and impact. These results underscore the potential for tailored interventions in improving outcomes in hypertensive CHF patients.
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